梁云；博士，教授，博士生导师

专业：有机化学 方向：有机合成

联系号码：18975106926 电子邮箱：yliang@hunnu.edu.cn

联系地址：湖南师范大学化学化工学院

教育背景：

1990-1994，湖南师范大学，化学教育专业，学士；

2002-2007，湖南师范大学，有机化学，博士，导师李金恒教授。

工作经历：

1994-2000，浏阳市第四中学，化学教师；

2000-2002，浏阳市田家炳实验中学，化学教师；

2009-2011，北京大学化学与分子工程学院，席振峰教授实验室，博士后研究；

2007-至今，湖南师范大学化学化工学院，教授，博士生导师。

研究方向：

过渡金属催化的偶联反应、串联反应的研究；

基于无机硫源合成硫杂环化合物的研究；

基于碳硅键的切断和构建的研究；

主持项目：

1. 国家自然科学基金面上项目：基于无机硫源的偶联-串联反应合成硫杂环化合物研究（21572051）；77.4万（2016-2019）

2. 国家自然科学基金面上项目：基于芳炔与碘叶立德反应及其应用的研究(21072054)；34万（结题）（2011-2013）

3. 教育部科学技术项目：基于芳炔与羧酸酯的反应及其在有机合成中应用研究（213027A）；50万（2013-2016）

4. 教育部博士点新教师基金：基于邻三甲基硅芳基三氟磺酸酯为芳炔的前体与碘叶立德反应的研究（20094306120003），3.6万（结题）（2010-2012）

5. 湖南省自然科学基金重点项目：基于芳炔与羧酸酯的反应及其在有机合成中应用研究(12JJ2009)；20万（结题）（2012-2015）

6. 湖南省教育厅科学技术重点项目：基于无机硫盐的双硫化反应合成硫醚和硫杂环化合物的研究（15A109）；8万（2015-2018）

7. 湖南省教育厅科学技术重点项目：基于芳炔与羧酸酯的反应及其在有机合成中应用研究(12A095)；8万（结题）（2012-2015）

8. 湖南省普通高校青年骨干教师，2万（2012）

9. 湖南师范大学优秀青年项目：基于芳炔与碘叶立德反应及其应用的研究 （ET21003）；10万（结题）（2010-2012）

10. 北京分子科学国家实验室开放基金：基于1,1-偕二卤-1,4-共轭二卤化合物多反应位点的交叉偶联-串联反应研究。5万（结题）（2012-2014）

获奖：

“过渡金属钯、铜催化构建C-C键和C-N键方法的研究” 湖南省2009年自然科学奖二等奖，排名第三

发表论文：

1. Li, W.; Chen, W.; Zhou, B.; Xu, Y.; Deng, G.; Liang, Y.*; Yang, Y.* NBE-Controlled Palladium-Catalyzed Interannular Selective C−H Silylation: Access to Divergent Silicon-Containing 1,1′-Biaryl-2- Acetamides, Org. Lett. 2019, 21, 2718.

2. Chen, L.; Min, H.; Zeng, W.; Zhu, X.; Liang, Y.*; Deng, G.*; Yang, Y.* Transition-Metal-Free Sulfuration/Annulation of Alkenes: Economical Access to Thiophenes Enabled by the Cleavage of Multiple C−H Bonds, Org. Lett. 2018, 20, 7392.

3. Yang, Y.; Zhou, B.; Zhu, X.; Deng, G.; Liang, Y.*; Yang, Y.* Palladium-Catalyzed Synthesis of Triphenylenes via Sequential C−H Activation and Decarboxylation, Org. Lett. 2018, 20, 5402.

4. Luo, X.; Xu, Y.; Xiao, G.; Liu, W.; Qian, C.; Deng, G.; Song, J.; Liang, Y.*; Yang, C.* Palladium-Catalyzed Tandem Reaction of Three Aryl Iodides Involving Triple C−H Activation, Org. Lett. 2018, 20, 2997.

5. Zhu, X.; Li, W.; Luo, X.; Deng, G.; Liang, Y.*; Liu, J.* A catalyst-free and additive-free method for the synthesis of benzothiazolethiones from o-iodoanilines, DMSO and potassium sulfide, Green Chem. 2018, 20, 1970.

6. Xiao, G.; Chen, L.; Zhou, B.; Deng, G.; Gong, J.; Liang, Y.* Palladium-Catalyzed Domino Heck/Silylation Reaction for the Synthesis of (2-Oxoindolin-3-yl)methylsilanes via Trapping of the s-Alkylpalladium Intermediates with Disilanes, Adv. Synth. Catal. 2018, 360, 3477.

7. Li, W.; Xiao, G.; Deng, G.; Liang, Y.* Pd-Catalyzed disilylation: an efficient route to 2,2’-bis(trimethylsilyl)biphenyls via trapping transient dibenzopalladacyclopentadienes with hexamethyldisilane, Org. Chem. Front. 2018, 5, 1488.

8. Xu, Y.; Liu, X.; Chen, W.; Deng, G.; Liang, Y.*; Yang, Y.* Palladium/Norbornene Chemistry: Synthesis of Norbornene-Containing Arylsilanes Involving Double C−Si Bond Formation, J. Org. Chem. 2018, 83, 13930.

9. Zheng, Z.; Chen, L.; Qian, C.; Zhu, X.; Yang, X.; Liu, J.*; Yang, Y.*; Liang, Y.* Copper-catalyzed synthesis of 2-acylbenzo[b]thiophenes from 3-(2-iodophenyl)-1-arylpropan-1-ones and potassium sulfide under aerobic conditions, Org. Biomol. Chem. 2018, 16, 8020.

10. Zhou, B.; Chen, W.; Yang, Y.; Yang, Y.; Deng, G.*; Liang, Y.* A radical cyclization cascade of 2-alkynylbenzonitriles with sodium arylsulfinates, Org. Biomol. Chem. 2018, 16, 7959.

11. Xiao, G.; Min, H.; Zheng, Z.; Deng, G.*; Liang, Y.* Copper-catalyzed three-component reaction of imidazo[1,2-a]pyridine with elemental sulfur and arylboronic acid to produce sulfenylimidazo[1,2-a]pyridines, Chin. Chem. Lett. 2018, 29, 1363.

12. Xiao, G.; Chen, L.; Deng, G.; Liu, J.*; Liang, Y.* Disilylation of N-(2-Halophenyl)-2-phenylacrylamides with hexamethyldisilane via trapping the spirocyclic palladacycles, Tetrahedron Lett. 2018, 58, 1836.

13. Liu, X.; Deng, G.*; Liang, Y.* Selective synthesis of benzo[4,5]imidazo[2,1-a]isoquinolines via coppercatalyzed tandem annulation of alkynylbenzonitriles with 2-Iodoanilines, Tetrahedron Lett. 2018, 58, 2844.

14. Liu, W.; Min, H.; Zhu, X.; Deng, G.*; Liang, Y.* Copper-catalyzed highly selective synthesis of 2-benzyl- and 2-benzylidene-substituted benzo[b]thiazinones from 2-iodophenylcinnamamides and potassium sulfide, Org. Biomol. Chem., 2017, 15, 9804.

15. Zhu, X.; Yang, Y.; Xiao, G.; Song, J.; Liang, Y.*; Deng, G.* Double C-S bond formation via C-H bond functionalization: synthesis of benzothiazoles and naphtho[2,1-d]thiazoles from N-substituted arylamines and elemental sulfur, Chem. Comm. 2017, 53, 11917.

16. Dang, P.; Zheng, Z.; Liang, Y.* Copper-Catalyzed C(sp3)−S Bond and C(sp2)−S Bond Cross-Coupling of 2‑(2-Iodobenzoyl) Substituted or 2‑(2-Iodobenzyl) Substituted 1,2,3,4-Tetrahydroisoquinolines with Potassium Sulfide: Synthesis of Isoquinoline-Fused 1,3-Benzothiazine Scaffolds, J. Org. Chem. 2017, 82, 2263.

17. Wu, L.; Deng, G.*; Liang, Y.* Synthesis of dibenzo[a,c]carbazoles from 2-(2-halophenyl)-indoles and iodobenzenes via palladium-catalyzed dual C–H functionalization, Org. Biomol. Chem., 2017, 15, 6808.

18. Zhou, S.; Xia, G.; Liang, Y.* Copper-catalyzed synthesis of 2-sulfenylindoles from indoline-2-thiones and aryl iodides, Tetrahedron, Lett. 2017, 58, 338.

19. Huang, H.; Dang, P.; Wu, L.; Liang, Y.*; Liu, J.* Copper-catalyzed synthesis of benzo[b]thiophene-fused imidazopyridines via the cleavage of C–H bond and C–X bond, Tetrahedron Lett. 2016, 57, 574.

20. Zheng, Z.; Deng, G.;* Liang, Y.* Synthesis of quinolines through copper-catalyzed intermolecular cyclization reaction from anilines and terminal acetylene esters, RSC Adv. 2016, 6, 103478.

21. Min, H.; Xiao, G.; Liu, W.; Liang, Y.* Copper-catalyzed synthesis of 2-aminobenzothiazoles from 2-iodophenyl isocyanides, potassium sulfide and amines, Org. Biomol. Chem., 2016, 14, 11088.

22. Dang, P.; Zeng, W.; Liang, Y.^* Copper-Catalyzed Three-Component Synthesis of Benzothiazolethiones from o‑Iodoanilines, Isocyanide, and Potassium Sulfide, Org. Lett. 2015, 17, 34.

23. Wu, L.; Huang, H.; Dang, P.; Liang, Y.*; Pi, S. Construction of benzo[a]carbazole derivatives via Diels–Alder reaction of arynes with vinylindoles, RSC Adv. 2015, 5, 64354.

24. Yang, Y.; Huang, H.; Liu, W.; Liang, Y.* Dual Role of Alkynyl Bromides in One-Step Synthesis of Bromo-Substituted Alkynyl Sulfides, Synthetic Communications 2015, 45, 86.

25. Zhang, X.; Zeng, W.; Yang, Y.; Huang, H.; Liang, Y.* Copper-Catalyzed Double C−S Bonds Formation via Different Paths: Synthesis of Benzothiazoles from N‑Benzyl-2-iodoaniline and Potassium Sulfide, Org. Lett. 2014, 16, 876.

26. Wu, L.; Huang, H.; Liang, Y.*; Cheng, Pi. Regio- and Stereoselective Synthesis of 2‑Amino-dienes via Decarboxylative Amination of 4‑(Ethoxycarbonyl)-2,3-allenols by TsNCO, J. Org. Chem. 2014, 79, 11264.

27. Yang,Y.; Huang, H.; Wu, L.; Liang, Y.* Palladium-catalyzed annulation of benzynes with N-substituted-N-(2-halophenyl)formamides: synthesis of phenanthridinones, Org. Biomol. Chem. 2014, 12, 5351.

28. Yang, Y.; Zhang, X.; Zeng, W.; Huang, H.; Liang, Y.* Copper catalyzed three-component synthesis of benzothiazolones from o-iodoanilines, DMF, and potassium sulfide, RSC Adv. 2014, 4, 6090.

29. Zeng, W.; Dang, P.; Zhang, X.; Liang, Y.*; Peng, C. Copper-catalyzed synthesis of 2-aminobenzothiazoles from carbodiimide and sodium hydrosulfide, RSC Adv. 2014, 4, 31003.

30. Huang, H.; Yang, Y.; Zhang, X.; Zeng, W. Liang, Y.*,Transition-metal-free approach to synthesis of indolines from N-(ortho-chloromethyl)aryl amides and iodoniumylides, Tetrahedron Lett. 2013, 54, 6049.

31. Yang, Y.; Huang, H.; Zhang, X.; Zeng, W.; Liang, Y.*,Synthesis of 2-Alkynyltetrahydrofuran Derivatives from Tetrahydrofuran and Alkynyl Bromides, Synthesis 2013, 3137.

32. Zhang, X.; Zeng, W.; Yang, Y.; Huang, H.; Liang, Y.*,Transition-Metal-Free Method for the Synthesis of Benzo[b]thiophenes from o-Halovinylbenzenes and K₂S via Direct S_NAr-Type Reaction, Cyclization, and Dehydrogenation Process, Synlett. 2013, 24, 1687.

33. Liang, Y.; Geng, W.; Wei, J.; Xi, Z.* Palladium-Catalyzed Intermolecular Coupling of 2-Silylaryl Bromides with Alkynes: Synthesis of Benzosiloles and Heteroarene-Fused Siloles by Catalytic Cleavage of the C(sp³)-Si Bond, Angew. Chem. Int. Ed. 2012, 51, 1934.

34. Liang, Y.; Geng, W.; Wei, J.; Ouyang, K.; Xi, Z.*Palladium-catalyzed SilylC(sp³)-H Bond Activation, Org. Biomol. Chem. 2012, 10, 1537.

35. Yang, Y.; Zhang, X.; Liang, Y.* Copper-catalyzed coupling of 1,2-dibromo-1-styrenes with sulfonamidesfor the preparation of ynamides, Tetrahedron Lett. 2012, 53, 6557.

36. Zhang, X.; Yang, Y.; Liang, Y.* Palladium-catalyzed double N-arylation to synthesize multisubstituteddibenzoazepine derivatives, Tetrahedron Lett. 2012, 53, 6406.

37. Liang, Y.; Zhang, S, Xi, Z.* Palladium-Catalyzed Synthesis of Benzosilolo[2,3-b]indoles via Cleavage of a C(sp³)-Si Bond and Consequent Intramolecular C(sp²)-Si Coupling, J. Am. Chem. Soc. 2011, 133, 9204.

38. Liang, Y.; Meng, T.; Zhang, H.; Xi, Z.* Palladium-catalyzed, one-pot, three-component approach to a-alkynylindoles from o-bromo-(2,2-dibromovinyl)benzenes, terminal alkynes and arylamines, Synlett. 2011, 911.

39. Pi, S.-F.; Yang, X.-H.; Huang, X.-C.; Liang, Y.*; Yang, G.-N.; Zhang, X.-H.; Li, J.-H.* Palladium-Catalyzed Cyclocarbonylation of Arynes with Methyl Allyl Carbonates: Selective Synthesis of 1H-Inden-1-ones, J. Org. Chem. 2010, 75, 3484.

40. Li, R.-J.; Pi, S.-F.; Liang, Y.*; Wang, Z.-Q.; Song, R.-J.; Chen, G.-X.; Li, J.-H.* Palladium-catalyzed annulations of arynes with 2-(2-iodophenoxy)-1-substituted ethanones Chem. Commun. 2010, 8183.

41. Liu, Y.-L.; Liang, Y.*; Pi, S.-F.; Li, J.-H.*, Selective Synthesis of o-Acylbenzylphosphonates by Insertion Reactions of Arynes into β-Ketophosphonates, J. Org. Chem. 2009, 74, 5691.

42. Pi, S.-F.; Tang, B.-X.; Li, J.-H.*; Liu, Y.-L.; Liang, Y.*, Palladium-Catalyzed Decarboxylative Coupling of Allylic Alkynoates with Arynes, Org. Lett. 2009, 11, 2309.

43. Liu, Y.-L.; Liang, Y.*; Pi, S.-F.; Huang, X.-C.; Li, J.-H.*, Palladium-Catalyzed Cocyclotrimerization of Allenes with Arynes: Selective Synthesis of Phenanthrenes, J. Org. Chem. 2009, 74, 3199.

44. Huang, X.-C.; Wang, F.; Liang, Y.*; Li, J.-H.*, Halopalladation/Decarboxylation/ Carbon-Carbon Forming Domino Process: Synthesis of 5-Halo-6-substituted Benzo[b]naphtho[2,1-d]furans, Org. Lett. 2009, 11, 1139.

45. Huang, X.-C.; Liu, Y.-L.; Liang, Y.*; Pi, S.-F.; Wang, F.; Li, J.-H.*, Cycloaddition of Arynes with Iodonium Ylides: A Mild and General Route for the Synthesis of Benzofuran Derivatives, Org. Lett. 2008, 10, 1525.

46. Xie, Y.-X.; Wang, J.; Li, J.-H.*; Liang, Y.*, Reusable and Ligand-Free Palladium-Catalyzed Suzuki-Miyaura Cross-Couplings of Aryl Halides with Arylboronic Acids in Tetra-n-butylammonium Bromide, Chin. J. Chem. 2008, 26, 2261.

47. Liang, Y.; Tao, L.-M.; Zhang, Y.-H.; Li, J.-H.*, Palladium-Catalyzed Cross-Coupling Reactions of 1,2-Diiodoalkenes with Terminal Alkynes: Selective Synthesis of Unsymmetrical Buta-1,3-diynes and 2-Ethynylbenzofurans, Synthesis. 2008, 3988.